Fatigue is recognized as a common state in palliative care and patients with advanced cancer experience it as the most distressing symptom affecting their quality of life123 patients characterize fatigue as a feeling of overwhelming exhaustion and lack of energy and enthusiasm. An analysis of fatigue in patients with cancer it reviews the concept of fatigue in health and disease constructs a fatigue assessment questionnaire and tests it and examines the relationship read more. Current literature shows that there is a gap in our knowledge about how tired ness fatigue in cancer patients should be defined and measured existing fa tigue related research in cancer patients shows conceptual and measurement differences piper 1993 there is no continuum of tiredness fatigue. The assessment of fatigue in cancer patients is beset by a number of methodological challenges the lack of a commonly agreed on definition of fatigue is perhaps the greatest challenge a definition proposed by cella and colleagues captures several of the more commonly described features of fatigue they define fatigue as a subjective state . Fatigue the most common symptom reported by people with cancer is associated with functional impairments and decrements in quality of life as drs lipman and lawrence have pointed out research on the etiology of cancer related fatigue is scant morrow et al1 conducted a detailed review of the evidence to support four hypotheses for cancer related fatigue and highlighted
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